| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | The Golden Compass | $552,007 | -32.5% | 108 | -2 | $5,111 | $1,516,295 | 2 | Warner Bros. | false | false |
| 2 | - | Bee Movie | $377,451 | - | 90 | - | $4,193 | $455,109 | 1 | Universal Pictures International (UPI) | true | false |
| 3 | - | Hitman | $171,943 | - | 29 | - | $5,929 | $171,943 | 1 | 20th Century Fox International | true | false |
| 4 | 2 | American Gangster | $115,884 | -42.6% | 37 | -15 | $3,132 | $1,958,795 | 5 | Universal Pictures International (UPI) | false | false |
| 5 | 3 | Why Men Don't Listen and Women Can't Read Maps | $114,425 | -13.2% | 22 | +1 | $5,201 | $282,014 | 2 | Rialto Distribution | false | false |
| 6 | 4 | Enchanted | $70,510 | -41.2% | 23 | -2 | $3,065 | $392,644 | 3 | Walt Disney Pictures | false | false |
| 7 | 6 | The Band's Visit | $68,877 | -19.5% | 11 | -1 | $6,261 | $192,710 | 2 | Xenix Filmdistribution | false | false |
| 8 | 5 | Ratatouille | $66,388 | -44.1% | 33 | -27 | $2,011 | $8,876,944 | 20 | Walt Disney Pictures | false | false |
| 9 | 7 | The Heartbreak Kid | $41,603 | -41.2% | 20 | -7 | $2,080 | $1,535,038 | 7 | Universal Pictures International (UPI) | false | false |
| 10 | - | The Fox and the Child | $33,966 | - | 9 | - | $3,774 | $43,598 | 1 | Frenetic Films | true | false |
| 11 | 13 | Atonement | $32,925 | -19.5% | 13 | - | $2,532 | $653,330 | 6 | Universal Pictures International (UPI) | false | false |
| 12 | 9 | Lions for Lambs | $32,561 | -36.4% | 19 | -1 | $1,713 | $768,983 | 6 | 20th Century Fox International | false | false |
| 13 | 10 | Gone Baby Gone | $32,320 | -36.1% | 9 | -2 | $3,591 | $159,924 | 3 | Walt Disney Pictures | false | false |
| 14 | 8 | Resident Evil: Extinction | $31,205 | -42.3% | 16 | +3 | $1,950 | $184,494 | 3 | Rialto Distribution | false | false |
| 15 | - | Natale in crociera | $27,958 | - | 3 | - | $9,319 | $27,958 | 1 | - | true | false |
| 16 | 11 | Earth | $24,993 | -46.6% | 22 | -4 | $1,136 | $1,084,507 | 10 | Frenetic Films | false | false |
| 17 | 16 | Michael Clayton | $20,177 | -28.3% | 8 | -1 | $2,522 | $145,120 | 11 | Rialto Distribution | false | false |
| 18 | - | The Secret of the Grain | $19,765 | - | 3 | - | $6,588 | $20,677 | 1 | Pathé | true | false |
| 19 | 14 | The Three Investigators and the Secret of Skeleton Island | $18,309 | -45.4% | 30 | -15 | $610 | $451,601 | 6 | Walt Disney Pictures | false | false |
| 20 | 19 | Free Rainer | $17,414 | -31.6% | 8 | - | $2,176 | $97,151 | 3 | Pathé | false | false |
