| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ratatouille | $875,286 | +6.9% | 102 | +5 | $8,581 | $5,871,201 | 12 | Walt Disney Pictures | false | false |
| 2 | - | I Now Pronounce You Chuck & Larry | $263,038 | - | 29 | - | $9,070 | $335,213 | 8 | Universal Pictures International (UPI) | false | false |
| 3 | 3 | Surf's Up | $126,244 | +13.2% | 57 | -3 | $2,214 | $760,953 | 6 | Walt Disney Pictures | false | false |
| 4 | 2 | The Bourne Ultimatum | $101,919 | -19.2% | 33 | -7 | $3,088 | $2,941,930 | 7 | Universal Pictures International (UPI) | false | false |
| 5 | 5 | Death at a Funeral | $79,023 | -1.1% | 23 | -1 | $3,435 | $1,294,129 | 8 | Ascot Elite Entertainment Group | false | false |
| 6 | 4 | Disturbia | $70,258 | -27.4% | 20 | -3 | $3,512 | $396,933 | 9 | Universal Pictures International (UPI) | false | false |
| 7 | 9 | Becoming Jane | $70,258 | +21.5% | 16 | +4 | $4,391 | $158,784 | 2 | Ascot Elite Entertainment Group | false | false |
| 8 | - | Rush Hour 3 | $67,706 | - | 10 | - | $6,770 | $1,474,364 | 10 | Warner Bros. | false | false |
| 9 | - | Lust, Caution | $64,650 | - | 10 | - | $6,465 | $64,650 | 1 | Ascot Elite Entertainment Group | true | false |
| 10 | 13 | Earth | $56,812 | +30.4% | 14 | +1 | $4,058 | $217,077 | 2 | Frenetic Films | false | false |
| 11 | 14 | Knocked Up | $56,382 | +35% | 20 | +1 | $2,819 | $1,081,442 | 9 | Universal Pictures International (UPI) | false | false |
| 12 | 6 | Tell | $48,996 | -32% | 30 | -7 | $1,633 | $655,141 | 4 | Universal Pictures International (UPI) | false | false |
| 13 | 10 | Persepolis | $48,458 | -15.7% | 14 | - | $3,461 | $463,712 | 9 | Filmcoopi | false | false |
| 14 | 12 | Stardust | $44,481 | -10.7% | 18 | +1 | $2,471 | $228,897 | 4 | Universal Pictures International (UPI) | false | false |
| 15 | 19 | The Assassination of Jesse James by the Coward Robert Ford | $42,134 | +16.3% | 8 | +1 | $5,266 | $97,876 | 2 | Warner Bros. | false | false |
| 16 | 11 | 99 Francs | $40,054 | -21.6% | 11 | -1 | $3,641 | $299,754 | 4 | Pathé | false | false |
| 17 | 16 | No Reservations | $38,863 | -3.9% | 21 | +2 | $1,850 | $796,306 | 6 | Warner Bros. | false | false |
| 18 | 8 | The Brave One | $38,666 | -37.3% | 27 | -7 | $1,432 | $525,751 | 4 | Warner Bros. | false | false |
| 19 | 18 | 1408 | $33,580 | -14.2% | 12 | -5 | $2,798 | $440,266 | 5 | Ascot Elite Entertainment Group | false | false |
| 20 | 7 | Superbad | $32,987 | -51.2% | 36 | +4 | $916 | $303,325 | 5 | Walt Disney Pictures | false | false |
