| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Rush Hour 3 | $200,344 | -43.5% | 71 | +1 | $2,821 | $682,441 | 2 | NuMetro Distribution | false | false |
| 2 | - | No Reservations | $114,401 | - | 46 | - | $2,486 | $114,401 | 1 | Warner Bros. | true | false |
| 3 | - | I Now Pronounce You Chuck & Larry | $87,747 | - | 62 | - | $1,415 | $87,747 | 1 | United International Pictures | true | false |
| 4 | 4 | Hairspray | $65,592 | -33.9% | 55 | - | $1,192 | $659,603 | 4 | NuMetro Distribution | false | false |
| 5 | 2 | Evan Almighty | $58,391 | -44.6% | 67 | -3 | $871 | $436,939 | 3 | United International Pictures | false | false |
| 6 | 3 | The Bourne Ultimatum | $57,970 | -43% | 69 | -5 | $840 | $1,271,344 | 5 | United International Pictures | false | false |
| 7 | 5 | License to Wed | $23,930 | -40.2% | 43 | -8 | $556 | $6,991,610 | 6 | Warner Bros. | false | false |
| 8 | 7 | Are We Done Yet? | $17,653 | -40.1% | 25 | -6 | $706 | $188,015 | 4 | Sony Pictures Releasing | false | false |
| 9 | 6 | The Simpsons Movie | $14,723 | -51.5% | 41 | -15 | $359 | $1,102,272 | 7 | 20th Century Fox International | false | false |
| 10 | - | The Hitcher | $13,602 | - | 23 | - | $591 | $13,602 | 1 | Ster-Kinekor Pictures | true | false |
| 11 | 8 | Transformers | $10,411 | -60.3% | 23 | -25 | $452 | $1,436,972 | 8 | United International Pictures | false | false |
| 12 | - | The Lives of Others | $8,228 | - | 4 | - | $2,057 | $8,228 | 1 | Ster-Kinekor Pictures | true | false |
| 13 | 11 | Becoming Jane | $7,375 | -42.5% | 18 | -4 | $409 | $176,940 | 5 | Ster-Kinekor Pictures | false | false |
| 14 | 15 | Half Nelson | $5,311 | -43% | 8 | -2 | $663 | $39,779 | 3 | Ster-Kinekor Pictures | false | false |
| 15 | - | Dhamaal | $5,251 | - | 4 | - | $1,312 | $5,251 | 1 | Ster-Kinekor Pictures | true | false |
| 16 | 12 | Live Free or Die Hard | $5,107 | -52.5% | 14 | -9 | $364 | $1,401,204 | 10 | 20th Century Fox International | false | false |
| 17 | 10 | Waitress | $4,988 | -66.6% | 9 | -3 | $554 | $55,474 | 3 | 20th Century Fox International | false | false |
| 18 | 14 | Mr. Brooks | $4,696 | -50.4% | 13 | -7 | $361 | $212,342 | 6 | NuMetro Distribution | false | false |
| 19 | 9 | Cake | $3,546 | -76.6% | 27 | -1 | $131 | $25,999 | 2 | Ster-Kinekor Pictures | false | false |
| 20 | 16 | Vacancy | $2,420 | -59.6% | 10 | -5 | $242 | $147,471 | 6 | Sony Pictures Releasing | false | false |
| 21 | - | The Astronaut Farmer | $2,167 | - | 10 | - | $216 | $2,167 | 1 | NuMetro Distribution | true | false |
| 22 | 19 | Curse of the Golden Flower | $1,703 | -43.3% | 7 | -2 | $243 | $51,951 | 6 | United International Pictures | false | false |
| 23 | 22 | Catch and Release | $1,473 | -26.6% | 4 | +1 | $368 | $44,232 | 7 | Sony Pictures Releasing | false | false |
| 24 | 23 | Black Snake Moan | $1,097 | -17.6% | 7 | +2 | $156 | $21,427 | 5 | United International Pictures | false | false |
| 25 | 20 | Stomp the Yard | $1,082 | -58.3% | 4 | -3 | $270 | $445,312 | 13 | Sony Pictures Releasing | false | false |
| 26 | 17 | Shrek the Third | $1,077 | -76.7% | 7 | -12 | $153 | $3,173,348 | 11 | United International Pictures | false | false |
| 27 | 21 | Pan's Labyrinth | $1,055 | -48.3% | 3 | - | $351 | $134,510 | 10 | United International Pictures | false | false |
| 28 | 25 | Hostel: Part II | $613 | -6.3% | 4 | +1 | $153 | $56,221 | 9 | Sony Pictures Releasing | false | false |
| 29 | 26 | Reign Over Me | $389 | -33.6% | 1 | -1 | $389 | $35,455 | 9 | Sony Pictures Releasing | false | false |
| 30 | 24 | Perfect Stranger | $279 | -69.8% | 1 | -1 | $279 | $651,226 | 21 | Sony Pictures Releasing | false | false |
