| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | The Simpsons Movie | $7,220,768 | - | 672 | - | $10,745 | $8,949,325 | 1 | 20th Century Fox International | true | false |
| 2 | 1 | Harry Potter and the Order of the Phoenix | $1,189,147 | -59.3% | 577 | -43 | $2,060 | $19,763,670 | 3 | Warner Bros. | false | false |
| 3 | 2 | Next | $979,740 | -44.6% | 323 | -2 | $3,033 | $3,489,263 | 2 | - | false | false |
| 4 | 3 | Pathfinder | $715,534 | -39.7% | 275 | +1 | $2,601 | $2,501,528 | 2 | 20th Century Fox International | false | false |
| 5 | 4 | Shrek the Third | $502,823 | -55.1% | 438 | -78 | $1,147 | $28,923,656 | 6 | Universal Pictures International (UPI) | false | false |
| 6 | - | Turistas | $400,258 | - | 177 | - | $2,261 | $400,258 | 1 | N/A | true | false |
| 7 | 5 | Transformers | $304,629 | -60.4% | 415 | -151 | $734 | $9,634,280 | 4 | Universal Pictures International (UPI) | false | false |
| 8 | 6 | Atasco en la nacional | $298,935 | -50.5% | 175 | - | $1,708 | $1,146,607 | 2 | N/A | false | false |
| 9 | 10 | Four Minutes | $126,317 | -19.7% | 62 | +2 | $2,037 | $369,258 | 2 | Alta Films | false | false |
| 10 | 8 | Café solo o con ellas | $117,278 | -52.5% | 187 | -42 | $627 | $2,730,985 | 5 | Buena Vista International | false | false |
| 11 | 9 | Ocean's Thirteen | $98,039 | -48.3% | 109 | -56 | $899 | $10,608,870 | 8 | Warner Bros. | false | false |
| 12 | 11 | Odette Toulemonde | $88,329 | -30.1% | 60 | -6 | $1,472 | $819,823 | 4 | Notro Films | false | false |
| 13 | - | O.F.N.I. | $86,201 | - | 21 | - | $4,104 | $126,829 | 2 | Independent Films | false | false |
| 14 | 7 | 28 Weeks Later | $86,059 | -66.9% | 158 | -109 | $544 | $4,415,777 | 5 | 20th Century Fox International | false | false |
| 15 | - | Lucky You | $79,209 | - | 50 | - | $1,584 | $79,209 | 1 | Warner Bros. | true | false |
| 16 | 13 | Pirates of the Caribbean: At World's End | $49,566 | -55.8% | 102 | -51 | $485 | $31,046,425 | 10 | Buena Vista International | false | false |
| 17 | 16 | Under the Stars | $33,567 | -30.5% | 34 | -9 | $987 | $1,203,201 | 7 | Notro Films | false | false |
| 18 | 12 | Gray Matters | $30,853 | -73% | 66 | -32 | $467 | $574,526 | 3 | - | false | false |
| 19 | 20 | Zodiac | $27,955 | -18% | 24 | -11 | $1,164 | $5,148,370 | 11 | Warner Bros. | false | false |
| 20 | - | My Best Friend | $24,839 | - | 19 | - | $1,307 | $314,488 | 5 | DeAPlaneta | false | false |
| 21 | 22 | Spider-Man 3 | $3,448 | -44% | 23 | -14 | $149 | $24,652,615 | 13 | Sony Pictures Releasing | false | false |
| 22 | 23 | Reign Over Me | $2,762 | -40.1% | 8 | - | $345 | $100,144 | 5 | Sony Pictures Releasing | false | false |
| 23 | 21 | Hostel: Part II | $1,635 | -82.9% | 6 | -16 | $272 | $1,975,940 | 7 | Sony Pictures Releasing | false | false |
| 24 | 24 | Stomp the Yard | $519 | -70.9% | 2 | -5 | $259 | $55,555 | 4 | Sony Pictures Releasing | false | false |
| 25 | 26 | Curse of the Golden Flower | $429 | +129.4% | 2 | - | $214 | $2,031,548 | 14 | Sony Pictures Releasing | false | false |
| 26 | 27 | Perfect Stranger | $308 | +96.2% | 2 | - | $154 | $5,658,763 | 16 | Sony Pictures Releasing | false | false |
