| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Norbit | $669,764 | - | 54 | - | $12,403 | $727,415 | 1 | Universal Pictures International (UPI) | true | false |
| 2 | 1 | Music and Lyrics | $373,963 | -24.3% | 96 | +1 | $3,895 | $1,140,630 | 2 | Warner Bros. | false | false |
| 3 | 2 | Hannibal Rising | $159,863 | -31.8% | 82 | - | $1,949 | $504,983 | 2 | Benelux Film Distributors | false | false |
| 4 | 4 | The Lives of Others | $152,098 | +9.3% | 30 | +8 | $5,069 | $586,350 | 3 | Cinemien | false | false |
| 5 | 3 | Night at the Museum | $133,347 | -30% | 100 | -1 | $1,333 | $2,774,562 | 5 | 20th Century Fox International | false | false |
| 6 | 5 | Blood Diamond | $92,744 | -22.9% | 64 | -10 | $1,449 | $2,968,980 | 8 | Warner Bros. | false | false |
| 7 | 10 | Ernst, Bobbie en de geslepen Onix | $78,666 | +30.5% | 108 | +1 | $728 | $1,666,986 | 5 | Independent Films | false | false |
| 8 | 7 | La Vie En Rose | $77,274 | +10.5% | 29 | - | $2,664 | $190,821 | 2 | RCV Film Distribution | false | false |
| 9 | 6 | Dreamgirls | $59,921 | -39.1% | 41 | - | $1,461 | $944,062 | 4 | Universal Pictures International (UPI) | false | false |
| 10 | 15 | Barnyard | $52,748 | +30.3% | 73 | -1 | $722 | $985,887 | 5 | Universal Pictures International (UPI) | false | false |
| 11 | - | Dennis P. | $43,853 | - | 31 | - | $1,414 | $77,949 | 1 | RCV Film Distribution | true | false |
| 12 | 9 | The Departed | $43,733 | -29.2% | 41 | -9 | $1,066 | $2,846,030 | 19 | Warner Bros. | false | false |
| 13 | 13 | The Last King of Scotland | $38,890 | -11.1% | 15 | - | $2,592 | $471,132 | 6 | 20th Century Fox International | false | false |
| 14 | 11 | The Good Shepherd | $34,750 | -37% | 33 | -12 | $1,053 | $740,599 | 5 | Benelux Film Distributors | false | false |
| 15 | 12 | Freedom Writers | $34,398 | -36.5% | 20 | - | $1,719 | $108,327 | 2 | Universal Pictures International (UPI) | false | false |
| 16 | 8 | Kicks | $32,644 | -52.8% | 35 | - | $932 | $491,057 | 3 | Independent Films | false | false |
| 17 | 19 | Notes on a Scandal | $31,651 | +14.6% | 12 | - | $2,637 | $245,776 | 4 | 20th Century Fox International | false | false |
| 18 | 17 | The Queen | $31,287 | -16.8% | 26 | - | $1,203 | $1,408,333 | 16 | A-Film Distribution | false | false |
| 19 | 20 | Arthur and the Invisibles | $29,890 | +59% | 70 | -8 | $427 | $754,493 | 7 | Independent Films | false | false |
| 20 | 18 | Babel | $25,298 | -23.8% | 25 | -7 | $1,011 | $2,190,510 | 20 | Independent Films | false | false |
