| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Ghost Rider | $29,417 | -64.4% | 8 | -1 | $3,677 | $134,900 | 2 | Alexandra Films | false | false |
| 2 | - | Little Miss Sunshine | $9,562 | - | 4 | - | $2,390 | $9,562 | 1 | Alexandra Films | true | false |
| 3 | 4 | Blood Diamond | $6,313 | +1.6% | 9 | - | $701 | $171,210 | 6 | Alexandra Films | false | false |
| 4 | 2 | Babel | $5,634 | -28.9% | 4 | - | $1,408 | $96,058 | 5 | Sunny Films | false | false |
| 5 | 5 | Breaking and Entering | $5,403 | -0.6% | 4 | - | $1,350 | $40,760 | 4 | Sunny Films | false | false |
| 6 | 3 | Volver | $4,311 | -36.5% | 5 | - | $862 | $32,566 | 3 | Big Bang Media | false | false |
| 7 | - | Fair Play | $3,793 | - | 5 | - | $758 | $3,793 | 1 | Alexandra Films | true | false |
| 8 | 25 | The Departed | $3,583 | +1,614.4% | 6 | +4 | $597 | $167,580 | 19 | Alexandra Films | false | false |
| 9 | 6 | The Illusionist | $3,534 | -24.4% | 5 | - | $706 | $20,789 | 3 | Diema Films | false | false |
| 10 | 12 | Valley of Flowers | $3,345 | +28.9% | 6 | +1 | $557 | $24,409 | 4 | Alexandra Films | false | false |
| 11 | 8 | The Queen | $3,330 | +0.7% | 3 | -1 | $1,110 | $14,682 | 3 | Prooptiki | false | false |
| 12 | 9 | The Pursuit of Happyness | $2,486 | -22.9% | 5 | - | $497 | $32,062 | 4 | Alexandra Films | false | false |
| 13 | - | Charlotte's Web | $2,427 | - | 3 | - | $809 | $2,427 | 1 | Prooptiki | true | false |
| 14 | 15 | Notes on a Scandal | $2,420 | +196.6% | 5 | - | $484 | $20,283 | 3 | Alexandra Films | false | false |
| 15 | 10 | Little Children | $2,353 | -21.3% | 3 | - | $784 | $6,664 | 2 | Alexandra Films | false | false |
| 16 | 7 | Letters from Iwo Jima | $2,325 | -29.7% | 4 | - | $581 | $7,297 | 2 | Alexandra Films | false | false |
| 17 | 11 | The Holiday | $1,651 | -39.2% | 5 | -1 | $330 | $76,124 | 7 | Prooptiki | false | false |
| 18 | 17 | Open Season | $1,243 | +73.1% | 3 | - | $414 | $125,370 | 17 | Alexandra Films | false | false |
| 19 | 16 | Happy Feet | $954 | +21.1% | 4 | - | $238 | $57,866 | 11 | Alexandra Films | false | false |
| 20 | 14 | Night at the Museum | $911 | +8.7% | 5 | - | $182 | $139,922 | 9 | Alexandra Films | false | false |
| 21 | 23 | Captain Alatriste: The Spanish Musketeer | $666 | +167.5% | 6 | -2 | $111 | $60,269 | 7 | Alexandra Films | false | false |
| 22 | 22 | Stormbreaker | $426 | +50.5% | 4 | -1 | $106 | $11,430 | 5 | Diema Films | false | false |
| 23 | 21 | The Prestige | $413 | +1.5% | 4 | -2 | $103 | $72,044 | 8 | Alexandra Films | false | false |
| 24 | 18 | Prime | $407 | -39.6% | 4 | +1 | $101 | $33,646 | 6 | Diema Films | false | false |
| 25 | 20 | DOA: Dead or Alive | $372 | -12.3% | 3 | -2 | $124 | $20,213 | 5 | Prooptiki | false | false |
| 26 | 19 | Wolfhound | $339 | -28.5% | 5 | - | $67 | $32,458 | 8 | Diema Films | false | false |
| 27 | 24 | Garfield: A Tail of Two Kitties | $176 | -26.1% | 1 | - | $176 | $158,015 | 28 | Alexandra Films | false | false |
| 28 | 27 | Eragon | $121 | -10.4% | 1 | - | $121 | $210,584 | 12 | Alexandra Films | false | false |
| 29 | 29 | Cars | $97 | +34.7% | 1 | - | $97 | $90,095 | 31 | Sunny Films | false | false |
| 30 | - | The Break-Up | $74 | - | 1 | - | $74 | $57,645 | 33 | Prooptiki | false | false |
| 31 | 33 | Children of Men | $67 | +91.4% | 1 | - | $67 | $33,281 | 17 | Prooptiki | false | false |
| 32 | 31 | Over the Hedge | $58 | -9.4% | 1 | -1 | $58 | $11,747 | 27 | Prooptiki | false | false |
| 33 | 35 | Flushed Away | $41 | +28.1% | 3 | +2 | $13 | $8,750 | 13 | Prooptiki | false | false |
| 34 | 26 | Sparrows in October | $33 | -80.8% | 2 | -2 | $16 | $769 | 3 | - | false | false |
| 35 | 30 | Apocalypto | $28 | -57.6% | 2 | -1 | $14 | $218,015 | 11 | Alexandra Films | false | false |
| 36 | - | The Night Listener | $19 | - | 1 | - | $19 | $6,121 | 9 | Prooptiki | false | false |
| 37 | 32 | The Devil Wears Prada | $14 | -68.2% | 1 | -1 | $14 | $157,354 | 21 | Alexandra Films | false | false |
