| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Night at the Museum | $5,670,564 | - | 473 | - | $11,988 | $5,670,564 | 1 | 20th Century Fox International | true | false |
| 2 | 3 | Babel | $1,192,949 | -7.5% | 213 | +14 | $5,600 | $9,369,675 | 5 | United International Pictures | false | false |
| 3 | 1 | Apocalypto | $1,165,988 | -40% | 283 | - | $4,120 | $3,642,150 | 2 | - | false | false |
| 4 | 4 | The Prestige | $674,410 | -40.1% | 312 | - | $2,161 | $4,022,469 | 3 | Warner Bros. | false | false |
| 5 | - | Dreamgirls | $632,794 | - | 183 | - | $3,457 | $632,794 | 1 | Universal Pictures International (UPI) | true | false |
| 6 | 2 | Rocky Balboa | $547,311 | -63.6% | 311 | -1 | $1,759 | $6,209,480 | 3 | 20th Century Fox International | false | false |
| 7 | 5 | Ekipo Ja | $482,142 | -56.4% | 240 | -1 | $2,008 | $1,747,633 | 2 | DeAPlaneta | false | false |
| 8 | 6 | Bobby | $359,529 | -35.5% | 174 | -3 | $2,066 | $1,081,487 | 2 | Manga Entertainment | false | false |
| 9 | - | Cry Wolf | $329,646 | - | 151 | - | $2,183 | $329,646 | 1 | Vértigo Films | true | false |
| 10 | 7 | The Kovak Box | $275,712 | -43.9% | 179 | -20 | $1,540 | $1,712,545 | 3 | - | false | false |
| 11 | 9 | Marie Antoinette | $258,422 | -35.1% | 111 | -1 | $2,328 | $2,490,499 | 4 | Sony Pictures Releasing | false | false |
| 12 | 8 | The Illusionist | $257,720 | -39.5% | 156 | -48 | $1,652 | $11,492,585 | 11 | - | false | false |
| 13 | 11 | Flags of Our Fathers | $217,422 | -36% | 163 | -2 | $1,333 | $2,403,581 | 4 | Warner Bros. | false | false |
| 14 | - | Fuerte Apache | $135,336 | - | 139 | - | $973 | $135,336 | 1 | Alta Films | true | false |
| 15 | 10 | Eragon | $121,434 | -68.1% | 197 | -84 | $616 | $13,782,479 | 7 | 20th Century Fox International | false | false |
| 16 | - | Pan's Labyrinth | $108,876 | - | 62 | - | $1,756 | $9,630,764 | 16 | Warner Bros. | false | false |
| 17 | 12 | Arthur and the Invisibles | $108,593 | -48.8% | 165 | -78 | $658 | $4,490,770 | 7 | New World Pictures | false | false |
| 18 | - | Little Miss Sunshine | $83,564 | - | 42 | - | $1,989 | $3,062,949 | 15 | 20th Century Fox International | false | false |
| 19 | - | The Departed | $79,148 | - | 58 | - | $1,364 | $11,893,096 | 14 | Warner Bros. | false | false |
