| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Happy Feet | $556,157 | - | 87 | - | $6,392 | $871,719 | 1 | Roadshow Films | true | false |
| 2 | 1 | Casino Royale | $347,029 | +11.2% | 87 | - | $3,988 | $2,669,698 | 4 | Sony Pictures Releasing | false | false |
| 3 | - | Night at the Museum | $326,880 | - | 75 | - | $4,358 | $462,356 | 1 | 20th Century Fox International | true | false |
| 4 | 8 | The Queen | $200,826 | +370.9% | 52 | +16 | $3,862 | $336,885 | 2 | Icon Film Distribution | false | false |
| 5 | 2 | Deja Vu | $149,834 | -7.5% | 45 | - | $3,329 | $401,569 | 2 | Buena Vista International | false | false |
| 6 | 3 | Eragon | $146,214 | -6.9% | 68 | -1 | $2,150 | $770,484 | 3 | 20th Century Fox International | false | false |
| 7 | 5 | The Holiday | $111,090 | -0.5% | 53 | - | $2,096 | $621,523 | 3 | United International Pictures | false | false |
| 8 | 4 | Charlotte's Web | $88,317 | -35% | 61 | +2 | $1,447 | $258,446 | 2 | United International Pictures | false | false |
| 9 | 7 | Borat | $60,843 | -17.5% | 30 | -18 | $2,028 | $74,241 | 6 | 20th Century Fox International | false | false |
| 10 | 13 | The Valet | $50,173 | +290.7% | 15 | - | $3,344 | $129,653 | 2 | Rialto Distribution | false | false |
| 11 | 6 | Flushed Away | $43,222 | -55.8% | 47 | -7 | $919 | $494,438 | 4 | United International Pictures | false | false |
| 12 | - | Marie Antoinette | $35,627 | - | 17 | - | $2,095 | $79,920 | - | Sony Pictures Releasing | - | false |
| 13 | 15 | Copying Beethoven | $12,988 | +60.7% | 16 | - | $811 | $26,873 | 2 | Hopscotch Films | false | false |
| 14 | - | Little Miss Sunshine | $9,632 | - | 10 | - | $963 | $596,950 | 12 | 20th Century Fox International | false | false |
| 15 | - | The White Massai | $9,413 | - | 8 | - | $1,176 | $170,793 | 9 | Hopscotch Films | false | false |
| 16 | 17 | Kenny | $6,594 | <0.1% | 10 | -7 | $659 | $322,516 | 8 | Madman Entertainment | false | false |
| 17 | 11 | Material Girls | $5,397 | -79% | 10 | -20 | $539 | $106,880 | 3 | Hoyts Distribution | false | false |
| 18 | 14 | The Departed | $2,714 | -73.3% | 11 | -8 | $246 | $789,148 | 7 | Warner Bros. | false | false |
| 19 | - | The Aura | $2,464 | - | 4 | - | $616 | $19,280 | 2 | Madman Entertainment | false | false |
| 20 | 19 | Five Days in September: The Rebirth of an Orchestra | $2,258 | +30.8% | 7 | -2 | $322 | $32,867 | 3 | Rialto Distribution | false | false |
