| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Anplagghed al cinema | $1,963,646 | -29.5% | 467 | -58 | $4,204 | $5,772,110 | 2 | Medusa Distribuzione | false | false |
| 2 | - | Happy Feet | $1,769,460 | - | 484 | - | $3,655 | $1,769,460 | 1 | Warner Bros. | true | false |
| 3 | - | The Wicker Man | $1,063,823 | - | 193 | - | $5,512 | $1,063,823 | 1 | Medusa Distribuzione | true | false |
| 4 | - | The Nativity Story | $727,024 | - | 437 | - | $1,663 | $727,233 | 1 | Eagle Pictures | true | false |
| 5 | 2 | My Super Ex-Girlfriend | $632,171 | -34.8% | 192 | -55 | $3,292 | $3,851,978 | 3 | 20th Century Fox International | false | false |
| 6 | - | The Roses of the Desert | $504,490 | - | 165 | - | $3,057 | $509,083 | 1 | Mikado Film | true | false |
| 7 | 3 | Marie Antoinette | $410,813 | -38.6% | 157 | -7 | $2,616 | $2,440,519 | 3 | Sony Pictures Releasing | false | false |
| 8 | 4 | The Departed | $258,765 | -53.5% | 90 | -90 | $2,875 | $11,321,720 | 6 | Medusa Distribuzione | false | false |
| 9 | - | Candy | $240,087 | - | 93 | - | $2,581 | $240,087 | 1 | Nexo | true | false |
| 10 | - | Deck the Halls | $234,173 | - | 99 | - | $2,365 | $234,173 | 1 | 20th Century Fox International | true | false |
| 11 | 5 | Children of Men | $211,550 | -60% | 104 | -112 | $2,034 | $2,038,904 | 3 | United International Pictures | false | false |
| 12 | 8 | Pan's Labyrinth | $158,518 | -58.2% | 93 | -58 | $1,704 | $715,363 | 2 | Warner Bros. | false | false |
| 13 | 7 | The Devil Wears Prada | $134,527 | -66.6% | 56 | -96 | $2,402 | $18,782,051 | 8 | 20th Century Fox International | false | false |
| 14 | 10 | The Wind that Shakes the Barley | $131,402 | -53.2% | 56 | -65 | $2,346 | $1,612,374 | 4 | BIM Distribuzione | false | false |
| 15 | 12 | Shortbus | $113,463 | -43.6% | 52 | -38 | $2,181 | $454,597 | 2 | BIM Distribuzione | false | false |
| 16 | - | Private Fears in Public Places | $104,877 | - | 12 | - | $8,739 | $104,877 | 1 | BIM Distribuzione | true | false |
| 17 | 9 | Over the Hedge | $96,913 | -73.6% | 108 | -126 | $897 | $9,158,948 | 6 | United International Pictures | false | false |
| 18 | 6 | You, Me and Dupree | $95,399 | -78.2% | 54 | -136 | $1,766 | $3,125,437 | 4 | United International Pictures | false | false |
| 19 | 14 | The Unknown Woman | $78,666 | -47.5% | 27 | -37 | $2,913 | $4,777,281 | 7 | Medusa Distribuzione | false | false |
| 20 | 11 | Quale amore | $61,814 | -70.6% | 43 | -77 | $1,437 | $727,282 | 3 | 01 Distribution | false | false |
