| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Pirates of the Caribbean: Dead Man's Chest | $2,331,897 | -51.4% | 787 | - | $2,963 | $30,551,665 | 3 | Buena Vista International | false | false |
| 2 | - | Garfield: A Tail of Two Kitties | $2,063,422 | - | 415 | - | $4,972 | $3,070,030 | 1 | 20th Century Fox International | true | false |
| 3 | - | Lady in the Water | $1,994,629 | - | 328 | - | $6,081 | $1,994,629 | 1 | Warner Bros. | true | false |
| 4 | - | United 93 | $804,303 | - | 134 | - | $6,002 | $1,075,010 | 1 | United International Pictures | true | false |
| 5 | 2 | An American Haunting | $550,911 | -47.1% | 242 | +1 | $2,276 | $2,129,101 | 2 | DeAPlaneta | false | false |
| 6 | - | The Night of the Sunflowers | $219,585 | - | 90 | - | $2,439 | $219,585 | 1 | Alta Films | true | false |
| 7 | 3 | Open Water 2: Adrift | $202,178 | -48.4% | 152 | -1 | $1,330 | $820,277 | 2 | On Pictures | false | false |
| 8 | 4 | Bandidas | $196,082 | -49.3% | 235 | -15 | $834 | $4,055,437 | 4 | 20th Century Fox International | false | false |
| 9 | - | Sex Crazy | $161,667 | - | 118 | - | $1,370 | $161,667 | 1 | Filmax | true | false |
| 10 | 5 | Poseidon | $151,429 | -55.6% | 191 | -147 | $792 | $8,408,706 | 5 | Warner Bros. | false | false |
| 11 | 9 | The Near East | $148,621 | -37.9% | 106 | - | $1,402 | $529,087 | 2 | 20th Century Fox International | false | false |
| 12 | 8 | The Sentinel | $136,242 | -44.2% | 125 | -87 | $1,089 | $5,964,551 | 6 | 20th Century Fox International | false | false |
| 13 | - | Sky Fighters | $105,243 | - | 102 | - | $1,031 | $105,243 | 1 | TriPictures | true | false |
| 14 | 6 | Talladega Nights: The Ballad of Ricky Bobby | $92,997 | -70.4% | 236 | -14 | $394 | $543,723 | 2 | Sony Pictures Releasing | false | false |
| 15 | 10 | Cars | $92,519 | -56.9% | 198 | -108 | $467 | $15,964,325 | 8 | Buena Vista International | false | false |
| 16 | 7 | Nacho Libre | $87,737 | -66.8% | 147 | -5 | $596 | $480,095 | 2 | United International Pictures | false | false |
| 17 | 12 | Unhitched | $86,727 | -55% | 140 | -8 | $619 | $392,925 | 2 | - | false | false |
| 18 | 11 | Silent Hill | $78,508 | -60.1% | 109 | -65 | $720 | $4,278,013 | 5 | United International Pictures | false | false |
| 19 | - | Breakfast on Pluto | $73,522 | - | 49 | - | $1,500 | $73,522 | 1 | Vértigo Films | true | false |
| 20 | 18 | C.R.A.Z.Y. | $49,222 | -9.1% | 28 | -2 | $1,757 | $429,990 | 4 | Golem Distribución | false | false |
