| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Pride & Prejudice | $1,102,941 | - | 227 | - | $4,858 | $1,488,250 | 1 | United International Pictures | true | false |
| 2 | 2 | In Her Shoes | $951,882 | -22% | 292 | +2 | $3,259 | $3,000,237 | 2 | 20th Century Fox International | false | false |
| 3 | 1 | The 40-Year-Old Virgin | $844,411 | -30.8% | 245 | -11 | $3,446 | $4,644,213 | 3 | United International Pictures | false | false |
| 4 | - | Into the Blue | $741,747 | - | 181 | - | $4,098 | $741,747 | 1 | 20th Century Fox International | true | false |
| 5 | 3 | Cinderella Man | $341,161 | -27.4% | 261 | -5 | $1,307 | $3,771,743 | 4 | Buena Vista International | false | false |
| 6 | 4 | Must Love Dogs | $237,052 | -37.6% | 174 | -3 | $1,362 | $1,762,660 | 3 | Warner Bros. | false | false |
| 7 | 6 | Wallace & Gromit: The Curse of the Were-Rabbit | $183,016 | -46.4% | 203 | -33 | $901 | $7,592,228 | 6 | United International Pictures | false | false |
| 8 | 10 | The Proposition | $175,059 | -19.3% | 63 | - | $2,778 | $913,877 | 3 | Sony Pictures Releasing | false | false |
| 9 | - | Dark Water 2005 Re-release | $167,893 | - | 76 | - | $2,209 | $167,893 | 1 | Buena Vista International | true | false |
| 10 | 7 | Night Watch 2005 Re-release | $145,640 | -49.1% | 113 | +1 | $1,288 | $537,878 | 2 | 20th Century Fox International | false | false |
| 11 | 9 | Serenity | $121,820 | -46.9% | 127 | -34 | $959 | $2,165,686 | 4 | United International Pictures | false | false |
| 12 | 8 | The Dukes of Hazzard | $116,309 | -50% | 126 | -71 | $923 | $7,481,747 | 6 | Roadshow Films | false | false |
| 13 | 16 | Little Fish | $100,896 | -9.1% | 59 | -2 | $1,710 | $2,175,539 | 7 | Icon Film Distribution | false | false |
| 14 | 11 | Charlie and the Chocolate Factory | $79,043 | -60.2% | 154 | -75 | $513 | $18,207,573 | 8 | Roadshow Films | false | false |
| 15 | 13 | The Adventures of Sharkboy and Lavagirl 3-D | $69,331 | -59.3% | 138 | -35 | $502 | $4,219,040 | 7 | Sony Pictures Releasing | false | false |
| 16 | 12 | Sky High | $67,321 | -62.8% | 118 | -70 | $570 | $4,755,135 | 7 | Buena Vista International | false | false |
| 17 | 18 | Enron: The Smartest Guys in the Room | $65,035 | -8.1% | 22 | +3 | $2,956 | $183,270 | 2 | Dendy Films | false | false |
| 18 | 14 | Deuce Bigalow: European Gigolo | $60,225 | -60.2% | 88 | -88 | $684 | $3,972,635 | 5 | Sony Pictures Releasing | false | false |
| 19 | 15 | Transporter 2 | $58,683 | -50% | 58 | -44 | $1,011 | $1,315,715 | 4 | 20th Century Fox International | false | false |
| 20 | 19 | Look Both Ways | $48,478 | +10.9% | 52 | +7 | $932 | $1,763,838 | 10 | Dendy Films | false | false |
