| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 2 | Wedding Crashers | $161,669 | -21.4% | 75 | +3 | $2,155 | $463,695 | 2 | A-Film Distribution | false | false |
| 2 | 1 | Mr. & Mrs. Smith | $155,462 | -36.7% | 100 | - | $1,554 | $4,042,757 | 6 | 20th Century Fox International | false | false |
| 3 | - | The Dukes of Hazzard | $143,846 | - | 50 | - | $2,876 | $145,149 | 1 | Warner Bros. | true | false |
| 4 | 4 | The Island | $109,347 | -41% | 86 | - | $1,271 | $1,329,649 | 4 | Warner Bros. | false | false |
| 5 | 3 | Deuce Bigalow: European Gigolo | $104,950 | -45.7% | 87 | - | $1,206 | $767,320 | 3 | Sony Pictures Releasing | false | false |
| 6 | 5 | Charlie and the Chocolate Factory | $104,139 | -41.2% | 136 | - | $765 | $4,498,137 | 7 | Warner Bros. | false | false |
| 7 | 6 | The Skeleton Key | $96,283 | -39.3% | 47 | - | $2,048 | $613,706 | 3 | United International Pictures | false | false |
| 8 | - | A Sound of Thunder | $66,946 | - | 50 | - | $1,338 | $70,972 | 1 | Moonlight Films | true | false |
| 9 | 7 | Zoop in Afrika | $45,401 | -39.9% | 99 | - | $458 | $2,384,396 | 8 | Independent Films | false | false |
| 10 | 8 | Kameleon 2 | $28,296 | -57.6% | 88 | -14 | $321 | $2,705,822 | 10 | Independent Films | false | false |
| 11 | 9 | Madagascar | $20,758 | -54% | 97 | -8 | $214 | $6,188,222 | 12 | United International Pictures | false | false |
| 12 | 10 | Monster-in-Law | $16,812 | -55.7% | 29 | -11 | $579 | $168,361 | 3 | Paradiso Entertainment | false | false |
| 13 | - | Manderlay | $14,741 | - | 13 | - | $1,133 | $16,607 | 1 | A-Film Distribution | true | false |
| 14 | 12 | The Hitchhiker's Guide to the Galaxy | $14,178 | -59.4% | 14 | -12 | $1,012 | $503,859 | 5 | Buena Vista International | false | false |
| 15 | 13 | The Jacket | $13,217 | -55.9% | 12 | - | $1,101 | $79,008 | 2 | Independent Films | false | false |
| 16 | 11 | War of the Worlds | $12,712 | -64% | 22 | -23 | $577 | $5,350,431 | 10 | United International Pictures | false | false |
| 17 | 15 | Guernsey | $12,353 | -30.5% | 7 | - | $1,764 | $36,282 | 2 | 1More Film | false | false |
| 18 | 14 | Herbie Fully Loaded | $11,888 | -51.5% | 62 | -13 | $191 | $1,652,747 | 9 | Buena Vista International | false | false |
| 19 | 19 | Changing Times | $10,386 | +13.2% | 12 | - | $865 | $310,014 | 11 | Inspire Pictures | false | false |
| 20 | 18 | Howl's Moving Castle | $8,950 | -25.5% | 8 | - | $1,118 | $49,662 | 3 | Paradiso Entertainment | false | false |
