| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Mr. & Mrs. Smith | $2,410,043 | -52% | 463 | +2 | $5,205 | $10,072,323 | 2 | 20th Century Fox International | false | false |
| 2 | - | A Sound of Thunder | $1,257,674 | - | 300 | - | $4,192 | $1,257,674 | 1 | - | true | false |
| 3 | - | Deuce Bigalow: European Gigolo | $849,760 | - | 275 | - | $3,090 | $849,760 | 1 | N/A | true | false |
| 4 | 2 | Charlie and the Chocolate Factory | $803,456 | -27.1% | 309 | +1 | $2,600 | $6,002,904 | 3 | Warner Bros. | false | false |
| 5 | - | Dark Water 2005 Re-release | $792,637 | - | 201 | - | $3,943 | $792,637 | 1 | Buena Vista International | true | false |
| 6 | 3 | Sin City | $450,617 | -43.4% | 321 | -4 | $1,403 | $4,782,660 | 3 | Buena Vista International | false | false |
| 7 | 4 | The Island | $443,267 | -44.3% | 330 | -96 | $1,343 | $8,086,252 | 4 | Warner Bros. | false | false |
| 8 | - | The Dukes of Hazzard | $305,948 | - | 248 | - | $1,233 | $305,948 | 1 | Warner Bros. | true | false |
| 9 | 6 | The Adventures of Sharkboy and Lavagirl 3-D | $202,509 | -45.3% | 150 | - | $1,350 | $876,682 | 2 | Sony Pictures Releasing | false | false |
| 10 | 7 | I Heart Huckabees | $168,613 | -48.8% | 188 | -1 | $896 | $1,503,202 | 3 | 20th Century Fox International | false | false |
| 11 | 8 | Ninette Undated Spain Release | $149,042 | -49.8% | 161 | -56 | $925 | $1,488,972 | 3 | N/A | false | false |
| 12 | 5 | Guess Who | $140,720 | -65.8% | 192 | -108 | $732 | $5,868,537 | 5 | 20th Century Fox International | false | false |
| 13 | 15 | Tout pour plaire | $88,838 | +13.9% | 47 | +2 | $1,890 | $579,567 | 4 | Golem Distribución | false | false |
| 14 | 10 | Herbie Fully Loaded | $78,525 | -61.5% | 174 | -103 | $451 | $3,890,133 | 5 | Buena Vista International | false | false |
| 15 | - | Real: The Movie | $77,540 | - | 105 | - | $738 | $77,540 | 1 | - | true | false |
| 16 | - | The Sisterhood of the Traveling Pants | $75,357 | - | 102 | - | $738 | $75,357 | 1 | TriPictures | true | false |
| 17 | 9 | Fantastic Four | $75,199 | -71.4% | 146 | -145 | $515 | $15,324,326 | 7 | 20th Century Fox International | false | false |
| 18 | - | The Night of the Brother | $69,626 | - | 71 | - | $980 | $69,626 | 1 | Alta Films | true | false |
| 19 | - | Are We There Yet? | $61,490 | - | 100 | - | $614 | $61,490 | 1 | Sony Pictures Releasing | true | false |
| 20 | 11 | The Amityville Horror | $60,925 | -70% | 86 | -120 | $708 | $5,790,768 | 6 | Buena Vista International | false | false |
