| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 4 | Madagascar | $451,154 | +75.5% | - | - | - | $2,577,825 | 4 | United International Pictures | false | false |
| 2 | 2 | Fantastic Four | $348,208 | +0.9% | - | - | - | $913,503 | 2 | 20th Century Fox International | false | false |
| 3 | 1 | War of the Worlds | $299,960 | -17.3% | - | - | - | $1,925,935 | 3 | United International Pictures | false | false |
| 4 | 3 | The Longest Yard | $249,261 | -6.6% | - | - | - | $684,477 | 2 | Sony Pictures Releasing | false | false |
| 5 | 7 | Herbie Fully Loaded | $162,505 | +138.7% | - | - | - | $506,223 | 3 | Buena Vista International | false | false |
| 6 | - | Are We There Yet? | $156,462 | - | - | - | - | $156,462 | 1 | Sony Pictures Releasing | true | false |
| 7 | - | House of Wax | $106,488 | - | - | - | - | $106,488 | 1 | Roadshow Films | true | false |
| 8 | 6 | Mr. & Mrs. Smith | $81,066 | +0.5% | - | - | - | $2,215,581 | 6 | 20th Century Fox International | false | false |
| 9 | 5 | Batman Begins | $76,793 | -6% | - | - | - | $1,410,098 | 5 | Warner Bros. | false | false |
| 10 | 11 | Pooh's Heffalump Movie | $73,066 | +136.6% | - | - | - | $179,789 | 2 | Buena Vista International | false | false |
| 11 | 8 | A Good Woman | $64,499 | +25.9% | - | - | - | $238,131 | 3 | Hopscotch Films | false | false |
| 12 | 13 | Star Wars: Episode III - Revenge of the Sith | $50,105 | +141.1% | - | - | - | $3,841,021 | 9 | 20th Century Fox International | false | false |
| 13 | 9 | Ladies in Lavender | $45,265 | +17% | - | - | - | $778,269 | 7 | Icon Film Distribution | false | false |
| 14 | 12 | The Sisterhood of the Traveling Pants | $29,685 | -1.6% | - | - | - | $90,861 | 2 | Warner Bros. | false | false |
| 15 | 10 | Monster-in-Law | $18,264 | -43.3% | - | - | - | $409,716 | 4 | Roadshow Films | false | false |
| 16 | 17 | Five Children and It | $15,705 | +154.8% | - | - | - | $39,066 | 2 | Icon Film Distribution | false | false |
| 17 | 14 | Hotel Rwanda | $13,711 | +6.8% | - | - | - | $150,382 | 5 | Roadshow Films | false | false |
| 18 | 15 | What the #$*! Do We (K)now!? 2005 Re-release | $9,637 | +23.8% | - | - | - | $94,829 | 9 | Hopscotch Films | false | false |
| 19 | 16 | Downfall | $7,714 | +12.7% | - | - | - | $177,639 | 7 | Hopscotch Films | false | false |
| 20 | 19 | Dear Frankie | $5,258 | +19.3% | - | - | - | $123,746 | 11 | Buena Vista International | false | false |
