| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Manual of Love | $3,887,449 | +5.1% | 484 | +2 | $8,031 | $9,422,213 | 2 | Filmauro | false | false |
| 2 | 2 | Hitch | $1,378,476 | +4.2% | 254 | -42 | $5,427 | $6,442,245 | 3 | Sony Pictures Releasing | false | false |
| 3 | - | Robots | $1,153,104 | - | 406 | - | $2,840 | $1,243,462 | 1 | 20th Century Fox International | true | false |
| 4 | - | Cose da pazzi | $823,185 | - | 153 | - | $5,380 | $823,185 | 1 | Medusa Distribuzione | true | false |
| 5 | 3 | A Series of Unfortunate Events | $724,083 | +17.9% | 198 | -16 | $3,656 | $1,629,115 | 2 | United International Pictures | false | false |
| 6 | 4 | Million Dollar Baby | $476,898 | -19.7% | 141 | -95 | $3,382 | $8,546,710 | 6 | 01 Distribution | false | false |
| 7 | 6 | Hostage | $420,348 | -10.4% | 151 | -50 | $2,783 | $1,086,181 | 2 | Medusa Distribuzione | false | false |
| 8 | - | Racing Stripes | $391,425 | - | 186 | - | $2,104 | $391,425 | 1 | Eagle Pictures | true | false |
| 9 | - | In Good Company | $334,273 | - | 145 | - | $2,305 | $334,273 | 1 | BIM Distribuzione | true | false |
| 10 | 7 | La terza stella | $289,351 | -32.1% | 107 | -109 | $2,704 | $1,911,030 | 3 | Medusa Distribuzione | false | false |
| 11 | 5 | Shark Tale | $260,960 | -45.7% | 152 | -117 | $1,716 | $10,941,885 | 5 | United International Pictures | false | false |
| 12 | - | Cursed | $242,084 | - | 79 | - | $3,064 | $242,084 | 1 | Buena Vista International | true | false |
| 13 | - | Suspect Zero | $195,454 | - | 57 | - | $3,429 | $195,454 | 1 | Sony Pictures Releasing | true | false |
| 14 | 10 | Pooh's Heffalump Movie | $194,985 | -5.9% | 160 | -7 | $1,218 | $502,021 | 2 | Buena Vista International | false | false |
| 15 | 8 | Hide and Seek | $180,913 | -54.1% | 64 | -146 | $2,826 | $2,190,965 | 3 | 20th Century Fox International | false | false |
| 16 | - | Tickets | $130,404 | - | 68 | - | $1,917 | $130,404 | 1 | Medusa Distribuzione | true | false |
| 17 | 11 | Sacred Heart | $116,864 | -34.9% | 54 | -36 | $2,164 | $3,649,548 | 5 | Medusa Distribuzione | false | false |
| 18 | 14 | Sideways | $85,284 | -7.1% | 34 | -9 | $2,508 | $2,999,173 | 6 | 20th Century Fox International | false | false |
| 19 | 9 | Constantine | $74,358 | -69% | 27 | -86 | $2,754 | $6,498,790 | 5 | Warner Bros. | false | false |
| 20 | 15 | Hotel Rwanda | $72,325 | -3.2% | 40 | -6 | $1,808 | $352,711 | 3 | Mikado Film | false | false |
