| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | - | Manual of Love | $3,698,156 | - | 482 | - | $7,672 | $3,707,000 | 1 | Filmauro | true | false |
| 2 | 1 | Hitch | $1,322,575 | -46.9% | 296 | +8 | $4,468 | $4,599,810 | 2 | Sony Pictures Releasing | false | false |
| 3 | - | A Series of Unfortunate Events | $614,318 | - | 214 | - | $2,870 | $614,318 | 1 | United International Pictures | true | false |
| 4 | 3 | Million Dollar Baby | $593,634 | -53.2% | 236 | -33 | $2,515 | $8,016,262 | 5 | 01 Distribution | false | false |
| 5 | 2 | Shark Tale | $480,823 | -68.4% | 269 | -102 | $1,787 | $10,835,035 | 4 | United International Pictures | false | false |
| 6 | - | Hostage | $468,994 | - | 201 | - | $2,333 | $470,534 | 1 | Medusa Distribuzione | true | false |
| 7 | 5 | La terza stella | $426,187 | -47.6% | 216 | +12 | $1,973 | $1,497,902 | 2 | Medusa Distribuzione | false | false |
| 8 | 4 | Hide and Seek | $394,493 | -57.5% | 210 | -56 | $1,878 | $1,608,665 | 2 | 20th Century Fox International | false | false |
| 9 | 6 | Constantine | $240,047 | -68.7% | 113 | -112 | $2,124 | $6,508,199 | 4 | Warner Bros. | false | false |
| 10 | - | Pooh's Heffalump Movie | $207,154 | - | 167 | - | $1,240 | $210,140 | 1 | Buena Vista International | true | false |
| 11 | 8 | Sacred Heart | $179,482 | -61% | 90 | -64 | $1,994 | $3,554,774 | 4 | Medusa Distribuzione | false | false |
| 12 | 7 | Meet the Fockers | $169,779 | -71.4% | 99 | -60 | $1,714 | $19,050,339 | 6 | United International Pictures | false | false |
| 13 | 13 | Life Is a Miracle | $99,175 | -40.9% | 58 | -3 | $1,709 | $634,896 | 3 | Fandango | false | false |
| 14 | 12 | Sideways | $91,807 | -48.6% | 43 | -7 | $2,135 | $2,332,649 | 5 | 20th Century Fox International | false | false |
| 15 | 16 | Hotel Rwanda | $74,728 | -32.4% | 46 | +4 | $1,624 | $238,801 | 2 | Mikado Film | false | false |
| 16 | 10 | The Clan | $73,601 | -74.6% | 88 | -92 | $836 | $453,363 | 2 | 01 Distribution | false | false |
| 17 | - | Touching the Void | $71,985 | - | 45 | - | $1,599 | $71,985 | 1 | Fandango | true | false |
| 18 | - | Kinsey | $62,273 | - | 39 | - | $1,596 | $223,646 | 1 | 20th Century Fox International | true | false |
| 19 | 14 | The Merchant of Venice | $61,502 | -55.8% | 36 | -24 | $1,708 | $4,806,042 | 6 | Istituto Luce | false | false |
| 20 | 9 | Blade: Trinity | $53,305 | -87.9% | 49 | -146 | $1,087 | $2,368,213 | 3 | Eagle Pictures | false | false |
