| Rank | LW | Release
| Gross | %± LW | Theaters | Change | Average | Total Gross | Weeks | Distributor
| New This Week
| Estimated
|
|---|
| 1 | 1 | Meet the Fockers | $4,393,970 | -23.2% | 495 | -2 | $8,876 | $12,405,969 | 2 | United International Pictures | false | false |
| 2 | 2 | Finding Neverland | $1,170,252 | -18.5% | 298 | -15 | $3,927 | $6,239,480 | 3 | Buena Vista International | false | false |
| 3 | 3 | The Merchant of Venice | $1,168,484 | +7.7% | 280 | +34 | $4,173 | $2,800,794 | 2 | Istituto Luce | false | false |
| 4 | - | Million Dollar Baby | $1,065,588 | - | 204 | - | $5,223 | $1,065,588 | 1 | 01 Distribution | true | false |
| 5 | - | The Forgotten | $933,152 | - | 200 | - | $4,665 | $933,152 | 1 | Sony Pictures Releasing | true | false |
| 6 | - | Sideways | $609,824 | - | 164 | - | $3,718 | $685,854 | 1 | 20th Century Fox International | true | false |
| 7 | 5 | Ma quando arrivano le ragazze? | $396,014 | -31.3% | 182 | -38 | $2,175 | $2,355,109 | 3 | 01 Distribution | false | false |
| 8 | 4 | The Aviator | $311,088 | -49.1% | 150 | -128 | $2,073 | $6,740,511 | 4 | 01 Distribution | false | false |
| 9 | 6 | Smalltown, Italy | $244,479 | -33.5% | 148 | -45 | $1,651 | $791,426 | 2 | Medusa Distribuzione | false | false |
| 10 | 10 | Around the World in 80 Days | $192,435 | -13.7% | 130 | -11 | $1,480 | $1,809,682 | 4 | Eagle Pictures | false | false |
| 11 | 9 | A Very Long Engagement | $167,339 | -33.5% | 141 | -12 | $1,186 | $545,087 | 2 | Warner Bros. | false | false |
| 12 | 7 | Elektra | $148,405 | -52.6% | 84 | -79 | $1,766 | $1,484,007 | 3 | 20th Century Fox International | false | false |
| 13 | - | The Heart Is Deceitful Above All Things | $96,753 | - | 54 | - | $1,791 | $96,753 | 1 | Minerva Film | true | false |
| 14 | 8 | Ladder 49 | $93,764 | -64.9% | 57 | -114 | $1,644 | $1,468,130 | 3 | Eagle Pictures | false | false |
| 15 | 11 | Saw | $61,951 | -58.3% | 39 | -28 | $1,588 | $6,437,627 | 6 | Eagle Pictures | false | false |
| 16 | 13 | House of Flying Daggers | $52,317 | -36.2% | 36 | -10 | $1,453 | $3,084,145 | 5 | BIM Distribuzione | false | false |
| 17 | 17 | Quai des illusions | $52,232 | -24.6% | 29 | - | $1,801 | $1,242,481 | 5 | Medusa Distribuzione | false | false |
| 18 | 12 | Alexander | $46,815 | -65.2% | 28 | -63 | $1,671 | $10,831,258 | 6 | Warner Bros. | false | false |
| 19 | 18 | Ray | $45,516 | -24.6% | 45 | +1 | $1,011 | $1,963,832 | 5 | United International Pictures | false | false |
| 20 | 16 | Come Into the Light | $42,698 | -41.6% | 38 | -11 | $1,123 | $1,516,078 | 5 | Mikado Film | false | false |
