| Rank | Movie Title (click to view) | Studio | Gross / Theaters | Total Gross / % of Total | Open |
| 1 | How the Grinch Stole Christmas | Uni. | $251,628,905 | 3,256 | $260,044,825 | 96.8% | 11/17/00 |
| 2 | Meet the Parents | Uni. | $161,146,255 | 2,697 | $166,244,045 | 96.9% | 10/6/00 |
| 3 | Erin Brockovich | Uni. | $125,595,205 | 3,070 | $125,595,205 | 100.0% | 3/17/00 |
| 4 | The Nutty Professor II: The Klumps | Uni. | $123,305,415 | 3,251 | $123,309,890 | 100.0% | 7/28/00 |
| 5 | U-571 | Uni. | $77,122,415 | 2,820 | $77,122,415 | 100.0% | 4/21/00 |
| 6 | Bring It On | Uni. | $68,337,590 | 2,466 | $68,379,000 | 99.9% | 8/25/00 |
| 7 | The Hurricane | Uni. | $50,542,241 | 2,148 | $50,699,241 | 99.7% | 12/29/99 |
| 8 | The Family Man | Uni. | $39,170,330 | 2,394 | $75,793,305 | 51.7% | 12/22/00 |
| 9 | The Flintstones in Viva Rock Vegas | Uni. | $35,268,275 | 3,125 | $35,268,275 | 100.0% | 4/28/00 |
| 10 | The Skulls | Uni. | $35,046,120 | 2,416 | $35,046,120 | 100.0% | 3/31/00 |
| 11 | The Watcher | Uni. | $28,946,615 | 2,777 | $28,946,615 | 100.0% | 9/8/00 |
| 12 | The Adventures of Rocky & Bullwinkle | Uni. | $26,005,820 | 2,482 | $26,005,820 | 100.0% | 6/30/00 |
| 13 | Billy Elliot | Focus | $17,037,706 | 510 | $21,995,263 | 77.5% | 10/13/00 |
| 14 | Man on the Moon | Uni. | $14,682,505 | 2,079 | $34,607,430 | 42.4% | 12/22/99 |
| 15 | Snow Falling on Cedars | Uni. | $14,316,301 | 1,155 | $14,417,593 | 99.3% | 12/22/99 |
| 16 | Screwed | Uni. | $7,027,345 | 1,761 | $7,027,345 | 100.0% | 5/12/00 |
| 17 | End of Days | Uni. | $4,349,937 | 1,063 | $66,889,043 | 6.5% | 11/24/99 |
| 18 | The Bone Collector | Uni. | $3,008,795 | 427 | $66,518,655 | 4.5% | 11/5/99 |
| 19 | Isn't She Great | Uni. | $2,962,465 | 750 | $2,962,465 | 100.0% | 1/28/00 |
| 20 | The Best Man | Uni. | $624,057 | 153 | $34,102,780 | 1.8% | 10/22/99 |
| 21 | Loving Jezebel | Focus | $72,190 | 74 | $72,190 | 100.0% | 10/27/00 |
| Summary of 21 Movies on Chart: |
| Totals: | $1,086,196,487 | - | - | - | - |
| Averages: | $51,723,642 | - | - | - | - |
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