| Rank | Release
| Genre
| Budget
| Running Time
| Gross | Theaters | Total Gross | Release Date | Distributor
| Estimated
|
|---|
| 1 | Toy Story 3 | - | - | - | $1,000,147 | 15 | $1,100,757 | Jun 17 | Walt Disney Pictures | false |
| 2 | Avatar | - | - | - | $950,261 | 18 | $1,454,156 | Dec 17 | 20th Century Fox International | false |
| 3 | Alice in Wonderland | - | - | - | $675,990 | 13 | $676,994 | Mar 4 | Walt Disney Pictures | false |
| 4 | Shrek Forever After | - | - | - | $616,101 | 16 | $644,133 | Jul 8 | Paramount Pictures International | false |
| 5 | Harry Potter and the Deathly Hallows: Part 1 | - | - | - | $591,996 | 33 | $616,542 | Nov 18 | Warner Bros. | false |
| 6 | Clash of the Titans | - | - | - | $525,046 | 17 | $525,046 | Apr 15 | Warner Bros. | false |
| 7 | Resident Evil: Afterlife | - | - | - | $400,474 | 16 | $400,474 | Sep 10 | Sony Pictures Releasing | false |
| 8 | Prince of Persia: The Sands of Time | - | - | - | $355,888 | 11 | $355,888 | May 27 | Walt Disney Pictures | false |
| 9 | The Chronicles of Narnia: The Voyage of the Dawn Treader | - | - | - | $326,472 | 22 | $429,153 | Dec 9 | 20th Century Fox International | false |
| 10 | Iron Man 2 | - | - | - | $311,086 | 14 | $311,086 | Apr 29 | Paramount Pictures International | false |
| 11 | How to Train Your Dragon | - | - | - | $282,504 | 13 | $282,504 | Mar 25 | Paramount Pictures International | false |
| 12 | Cats & Dogs: The Revenge of Kitty Galore | - | - | - | $273,148 | 12 | $273,148 | Aug 19 | Warner Bros. | false |
| 13 | Despicable Me | - | - | - | $265,912 | 14 | $265,912 | Jul 29 | Universal Pictures International (UPI) | false |
| 14 | Legend of the Guardians: The Owls of Ga'Hoole | - | - | - | $255,935 | 17 | $255,935 | Sep 30 | Warner Bros. | false |
| 15 | The Sorcerer's Apprentice | - | - | - | $252,222 | 8 | $252,222 | Jul 16 | Walt Disney Pictures | false |
| 16 | The Karate Kid | - | - | - | $249,809 | 11 | $249,809 | Jun 24 | Sony Pictures Releasing | false |
| 17 | The Last Airbender | - | - | - | $237,461 | 13 | $237,461 | Aug 26 | Paramount Pictures International | false |
| 18 | Megamind | - | - | - | $231,311 | 14 | $278,640 | Dec 2 | Paramount Pictures International | false |
| 19 | Paranormal Activity 2 | - | - | - | $210,794 | 7 | $210,794 | Nov 4 | Paramount Pictures International | false |
| 20 | The Twilight Saga: New Moon | - | - | - | $203,967 | 10 | $203,967 | Jan 1 | - | false |
| 21 | Tooth Fairy | - | - | - | $174,809 | 8 | $174,809 | Jan 14 | 20th Century Fox International | false |
| 22 | Alvin and the Chipmunks: The Squeakquel | - | - | - | $168,315 | 10 | $271,964 | Dec 25 | 20th Century Fox International | false |
| 23 | Inception | - | - | - | $163,443 | 10 | $163,443 | Aug 5 | Warner Bros. | false |
| 24 | The Twilight Saga: Eclipse | - | - | - | $160,671 | 13 | $160,671 | Sep 23 | - | false |
| 25 | Grown Ups | - | - | - | $151,699 | 8 | $151,699 | Aug 12 | Sony Pictures Releasing | false |
| 26 | Pocholo y su Marida - amor a lo gorrión | - | - | - | $151,511 | 8 | $179,924 | Nov 25 | - | false |
| 27 | Robin Hood | - | - | - | $146,020 | 10 | $146,020 | May 20 | Universal Pictures International (UPI) | false |
| 28 | A Nightmare on Elm Street | - | - | - | $144,745 | 6 | $144,745 | May 13 | Warner Bros. | false |
| 29 | The Princess and the Frog | - | - | - | $138,395 | 8 | $138,395 | Jan 1 | Walt Disney Pictures | false |
| 30 | Gulliver's Travels | - | - | - | $137,503 | 15 | $442,038 | Dec 23 | 20th Century Fox International | false |
| 31 | Old Dogs | - | - | - | $137,191 | 5 | $137,191 | Jan 28 | Walt Disney Pictures | false |
| 32 | Sherlock Holmes | - | - | - | $133,079 | 7 | $133,079 | Jan 14 | Warner Bros. | false |
| 33 | The Wolfman | - | - | - | $131,803 | 12 | $142,291 | Feb 11 | Universal Pictures International (UPI) | false |
| 34 | Tron: Legacy | - | - | - | $122,207 | 16 | $193,227 | Dec 16 | Walt Disney Pictures | false |
| 35 | Piranha 3D | - | - | - | $111,962 | 6 | $111,962 | Sep 16 | - | false |
| 36 | Percy Jackson & the Olympians: The Lightning Thief | - | - | - | $110,577 | 12 | $121,320 | Feb 11 | 20th Century Fox International | false |
| 37 | Life as We Know It | - | - | - | $105,274 | 5 | $105,274 | Oct 21 | Warner Bros. | false |
| 38 | Search for Paradise | - | - | - | $101,879 | 6 | $101,879 | Jan 7 | - | false |
| 39 | Knight and Day 2010 Re-release | - | - | - | $94,395 | 10 | $94,395 | Jul 22 | 20th Century Fox International | false |
| 40 | Marmaduke | - | - | - | $94,267 | 8 | $94,267 | Jun 3 | 20th Century Fox International | false |
| 41 | The Book of Eli | - | - | - | $84,676 | 6 | $84,676 | Mar 18 | Sony Pictures Releasing | false |
| 42 | Salt | - | - | - | $84,397 | 10 | $84,397 | Aug 19 | Sony Pictures Releasing | false |
| 43 | Legion | - | - | - | $82,430 | 6 | $82,430 | Apr 1 | Sony Pictures Releasing | false |
| 44 | Predators | - | - | - | $81,431 | 8 | $81,431 | Aug 5 | 20th Century Fox International | false |
| 45 | Devil | - | - | - | $80,330 | 6 | $90,168 | Nov 25 | Universal Pictures International (UPI) | false |
| 46 | Eat Pray Love | - | - | - | $75,315 | 7 | $75,315 | Oct 28 | Sony Pictures Releasing | false |
| 47 | Sex and the City 2 | - | - | - | $72,913 | 6 | $72,913 | Jun 3 | Warner Bros. | false |
| 48 | The Hurt Locker | - | - | - | $72,208 | 2 | $72,208 | Feb 18 | - | false |
| 49 | Vampires Suck | - | - | - | $71,452 | 5 | $71,452 | Oct 7 | 20th Century Fox International | false |
| 50 | Paranormal Activity | - | - | - | $71,293 | 4 | $71,293 | Mar 25 | - | false |
| 51 | Due Date | - | - | - | $65,265 | 7 | $65,265 | Nov 4 | Warner Bros. | false |
| 52 | The Bounty Hunter | - | - | - | $59,172 | 6 | $59,172 | May 6 | Sony Pictures Releasing | false |
| 53 | Solomon Kane | - | - | - | $57,968 | 5 | $57,968 | Oct 7 | - | false |
| 54 | Garfield's Pet Force | - | - | - | $56,251 | 3 | $56,251 | Oct 28 | - | false |
| 55 | Wall Street: Money Never Sleeps | - | - | - | $49,496 | 6 | $49,496 | Sep 23 | 20th Century Fox International | false |
| 56 | The A-Team | - | - | - | $49,300 | 8 | $49,300 | Jun 24 | 20th Century Fox International | false |
| 57 | The Strangers | - | - | - | $46,347 | 2 | $46,347 | Jul 1 | - | false |
| 58 | Edge of Darkness | - | - | - | $45,517 | 7 | $45,517 | Feb 25 | Warner Bros. | false |
| 59 | The Tourist | - | - | - | $45,022 | 6 | $163,402 | Dec 23 | Sony Pictures Releasing | false |
| 60 | Date Night | - | - | - | $44,887 | 5 | $44,887 | May 13 | 20th Century Fox International | false |
| 61 | Furry Vengeance | - | - | - | $39,897 | 5 | $39,897 | Oct 28 | - | false |
| 62 | Valentine's Day | - | - | - | $39,760 | 5 | $45,439 | Feb 11 | Warner Bros. | false |
| 63 | Planet 51 | - | - | - | $39,030 | 3 | $39,030 | Jan 7 | - | false |
| 64 | The Back-up Plan | - | - | - | $38,501 | 4 | $38,501 | Jul 1 | Sony Pictures Releasing | false |
| 65 | The Blind Side | - | - | - | $35,097 | 5 | $35,097 | Mar 18 | Warner Bros. | false |
| 66 | Halloween II | - | - | - | $34,719 | 4 | $34,719 | Oct 28 | - | false |
| 67 | The Town | - | - | - | $34,262 | 4 | $34,262 | Oct 14 | Warner Bros. | false |
| 68 | Unrest 2009 Re-release | - | - | - | $33,862 | 2 | $33,862 | May 6 | - | false |
| 69 | Invictus | - | - | - | $33,539 | 4 | $33,539 | Feb 4 | Warner Bros. | false |
| 70 | The Social Network | - | - | - | $32,987 | 5 | $43,052 | Dec 2 | Sony Pictures Releasing | false |
| 71 | The Other Guys | - | - | - | $32,469 | 4 | $32,469 | Oct 21 | Sony Pictures Releasing | false |
| 72 | Toy Story 2 2009 Re-release | - | - | - | $32,064 | 4 | $32,064 | Feb 18 | Walt Disney Pictures | false |
| 73 | Killers | - | - | - | $31,673 | 5 | $31,673 | Nov 25 | - | false |
| 74 | Regresa | - | - | - | $30,751 | 5 | $30,751 | Apr 22 | - | false |
| 75 | New in Town | - | - | - | $29,838 | 3 | $29,838 | Apr 8 | - | false |
| 76 | Saw VI | - | - | - | $27,674 | 4 | $27,674 | Feb 4 | Walt Disney Pictures | false |
| 77 | Nine | - | - | - | $27,248 | 4 | $27,248 | Jan 21 | Sony Pictures Releasing | false |
| 78 | Shutter Island | - | - | - | $26,827 | 7 | $26,827 | May 27 | Paramount Pictures International | false |
| 79 | The Appeared | - | - | - | $26,029 | 1 | $26,029 | Jun 10 | - | false |
| 80 | Zombieland | - | - | - | $25,763 | 6 | $25,763 | Jan 7 | Sony Pictures Releasing | false |
| 81 | Going the Distance | - | - | - | $25,694 | 4 | $25,694 | Sep 16 | Warner Bros. | false |
| 82 | The Expendables | - | - | - | $24,898 | 6 | $24,898 | Dec 2 | - | false |
| 83 | Scar | - | - | - | $22,878 | 2 | $22,878 | May 20 | - | false |
| 84 | Toy Story 2009 Re-release | - | - | - | $22,007 | 4 | $32,214 | Feb 11 | Walt Disney Pictures | false |
| 85 | Dear John | - | - | - | $21,271 | 4 | $21,271 | Apr 8 | Sony Pictures Releasing | false |
| 86 | Case 39 | - | - | - | $21,138 | 5 | $21,138 | Jun 10 | Paramount Pictures International | false |
| 87 | Cirque du Freak: The Vampire's Assistant | - | - | - | $20,824 | 7 | $20,824 | Mar 11 | Universal Pictures International (UPI) | false |
| 88 | Igor | - | - | - | $20,766 | 4 | $20,766 | Sep 9 | - | false |
| 89 | Did You Hear About the Morgans? | - | - | - | $19,375 | 4 | $19,375 | Mar 11 | Sony Pictures Releasing | false |
| 90 | The Salvation Poem | - | - | - | $19,267 | 3 | $31,883 | Apr 15 | - | false |
| 91 | The Imaginarium of Doctor Parnassus | - | - | - | $19,019 | 4 | $19,019 | Mar 25 | Sony Pictures Releasing | false |
| 92 | My Best Friend's Girl | - | - | - | $18,593 | 6 | $18,593 | Sep 2 | - | false |
| 93 | Drag Me to Hell | - | - | - | $18,328 | 5 | $18,328 | Jan 28 | Universal Pictures International (UPI) | false |
| 94 | All About Steve | - | - | - | $18,159 | 4 | $18,159 | Feb 25 | 20th Century Fox International | false |
| 95 | Whiteout | - | - | - | $16,555 | 3 | $31,677 | Dec 25 | Warner Bros. | false |
| 96 | Up in the Air | - | - | - | $14,100 | 8 | $14,100 | Mar 4 | Paramount Pictures International | false |
| 97 | Machete | - | - | - | $13,891 | 4 | $13,891 | Nov 11 | Sony Pictures Releasing | false |
| 98 | Remember Me | - | - | - | $13,246 | 4 | $13,246 | Jul 8 | - | false |
| 99 | The Forbidden Kingdom 2010 Re-release | - | - | - | $12,429 | 2 | $12,429 | Sep 16 | - | false |
| 100 | Sorority Row | - | - | - | $12,324 | 6 | $12,324 | Feb 25 | - | false |
| 101 | Nanny McPhee Returns | - | - | - | $12,187 | 7 | $16,920 | Dec 23 | United International Pictures | false |
| 102 | Ninja Assassin | - | - | - | $11,662 | 4 | $11,662 | Feb 18 | Warner Bros. | false |
| 103 | Letters to Juliet | - | - | - | $11,575 | 4 | $11,575 | Sep 9 | - | false |
| 104 | The Men Who Stare at Goats | - | - | - | $11,396 | 4 | $11,396 | Apr 22 | Sony Pictures Releasing | false |
| 105 | Takers 2010 Re-release | - | - | - | $11,161 | 4 | $11,161 | Nov 25 | Sony Pictures Releasing | false |
| 106 | Armored | - | - | - | $10,323 | 4 | $10,323 | Jan 28 | Sony Pictures Releasing | false |
| 107 | 2012 | - | - | - | $10,167 | 12 | $739,891 | Nov 12 | Sony Pictures Releasing | false |
| 108 | Two Lovers | - | - | - | $10,091 | 3 | $10,091 | Aug 26 | - | false |
| 109 | Couples Retreat | - | - | - | $9,736 | 4 | $9,736 | Feb 25 | Universal Pictures International (UPI) | false |
| 110 | Astro Boy | - | - | - | $9,353 | 4 | $9,353 | Apr 8 | - | false |
| 111 | It's Complicated | - | - | - | $8,096 | 4 | $9,407 | Jun 17 | Universal Pictures International (UPI) | false |
| 112 | Paintball | - | - | - | $8,020 | 3 | $8,020 | Oct 21 | - | false |
| 113 | Transporter 3 | - | - | - | $7,893 | 3 | $7,893 | Jan 7 | - | false |
| 114 | Undertow | - | - | - | $7,773 | 5 | $7,773 | Sep 2 | - | false |
| 115 | Green Zone 2010 Re-release | - | - | - | $7,751 | 4 | $7,751 | Aug 12 | Universal Pictures International (UPI) | false |
| 116 | Everybody's Fine | - | - | - | $6,703 | 2 | $6,703 | Mar 18 | Walt Disney Pictures | false |
| 117 | The Secret in Their Eyes | - | - | - | $6,517 | 2 | $19,137 | Mar 25 | - | false |
| 118 | Smother | - | - | - | $6,276 | 2 | $6,276 | Oct 7 | - | false |
| 119 | A Christmas Carol | - | - | - | $5,813 | 7 | $127,367 | Dec 3 | Walt Disney Pictures | false |
| 120 | Tinker Bell and the Lost Treasure | - | - | - | $5,643 | 4 | $5,643 | Jan 14 | Walt Disney Pictures | false |
| 121 | Flawless | - | - | - | $4,738 | 2 | $4,738 | Feb 18 | - | false |
| 122 | Be Kind Rewind | - | - | - | $4,645 | 2 | $4,645 | Jun 10 | - | false |
| 123 | Good Business | - | - | - | $4,483 | 4 | $4,483 | Nov 11 | - | false |
| 124 | Precious | - | - | - | $4,326 | 3 | $4,326 | Jun 10 | - | false |
| 125 | Paris 36 | - | - | - | $3,764 | 2 | $3,764 | Sep 30 | - | false |
| 126 | Transsiberian | - | - | - | $2,641 | 3 | $2,641 | Jun 10 | - | false |
| 127 | Bordertown 2010 Re-release | - | - | - | $2,628 | 2 | $2,628 | Mar 11 | - | false |
| 128 | The Lovely Bones | - | - | - | $2,611 | 5 | $2,611 | Apr 15 | Paramount Pictures International | false |
| 129 | Happy-Go-Lucky | - | - | - | $2,408 | 3 | $2,408 | May 6 | - | false |
| 130 | Julie & Julia | - | - | - | $2,335 | 4 | $8,105 | Dec 25 | Sony Pictures Releasing | false |
| 131 | Broken Embraces | - | - | - | $2,124 | 4 | $2,124 | Apr 22 | United International Pictures | false |
| 132 | Land of the Lost | - | - | - | $2,087 | 5 | $20,061 | Dec 25 | Universal Pictures International (UPI) | false |
| 133 | Love Happens | - | - | - | $1,978 | 2 | $1,978 | Sep 16 | - | false |
| 134 | Two Brothers 2010 Re-release | - | - | - | $1,958 | 2 | $1,958 | Jul 15 | - | false |
| 135 | My Mom's New Boyfriend | - | - | - | $1,605 | 1 | $1,605 | Aug 26 | - | false |
| 136 | The Host 2010 Re-release | - | - | - | $1,546 | 2 | $1,546 | Feb 25 | - | false |
| 137 | An Education | - | - | - | $1,448 | 2 | $1,448 | Mar 25 | Sony Pictures Releasing | false |
| 138 | Diary of a Nymphomaniac | - | - | - | $1,416 | 1 | $1,416 | Aug 12 | - | false |
| 139 | Bangkok Dangerous | - | - | - | $1,236 | 2 | $1,236 | Sep 30 | - | false |
| 140 | Swing Vote 2010 Re-release | - | - | - | $1,084 | 2 | $1,084 | Oct 14 | - | false |
| 141 | Carancho | - | - | - | $1,054 | 2 | $1,054 | Oct 21 | - | false |
| 142 | Cowards 2010 Re-release | - | - | - | $1,049 | 2 | $1,049 | Mar 25 | - | false |
| 143 | Ponyo | - | - | - | $1,024 | 1 | $1,024 | Apr 8 | - | false |
| 144 | Paranoid Park | - | - | - | $973 | 2 | $973 | Feb 18 | - | false |
| 145 | The Unknown Woman 2010 Re-release | - | - | - | $925 | 2 | $12,780 | Jul 15 | - | false |
| 146 | The Zone | - | - | - | $919 | 1 | $919 | May 27 | - | false |
| 147 | Alone with Her 2010 Re-release | - | - | - | $913 | 2 | $913 | Nov 11 | - | false |
| 148 | Cassandra's Dream 2010 Re-release | - | - | - | $901 | 1 | $1,261 | Dec 23 | - | false |
| 149 | Eastern Promises 2010 Re-release | - | - | - | $705 | 1 | $705 | Nov 11 | - | false |
| 150 | The Maid | - | - | - | $649 | 1 | $649 | Oct 14 | - | false |
| 151 | Vicky Cristina Barcelona | - | - | - | $648 | 1 | $648 | Jul 15 | - | false |
| 152 | Gods 2010 Re-release | - | - | - | $562 | 1 | $562 | Nov 11 | - | false |
| 153 | The Time Traveler's Wife | - | - | - | $285 | 4 | $12,138 | Dec 17 | Warner Bros. | false |
| 154 | A Boyfriend for My Wife | - | - | - | $260 | 1 | $260 | Oct 14 | - | false |
| 155 | Irina Palm 2010 Re-release | - | - | - | $241 | 1 | $241 | Jul 8 | - | false |
