Franchise: Despicable Me
| Rank | Release | Lifetime Gross | Max Theaters | Opening | Open Th | Release Date | Distributor |
|---|---|---|---|---|---|---|---|
| 1 | Minions: The Rise of Gru | $370,270,765 | 4,427 | $107,010,140 | 4,391 | Jul 1, 2022 | Universal Pictures |
| 2 | Despicable Me 2 | $368,065,385 | 4,003 | $83,517,315 | 3,997 | Jul 3, 2013 | Universal Pictures |
| 3 | Despicable Me 4 | $361,004,205 | 4,449 | $75,009,210 | 4,428 | Jul 3, 2024 | Universal Pictures |
| 4 | Minions | $336,045,770 | 4,311 | $115,718,405 | 4,301 | Jul 10, 2015 | Universal Pictures |
| 5 | Despicable Me 3 | $264,624,300 | 4,535 | $72,434,025 | 4,529 | Jun 30, 2017 | Universal Pictures |
| 6 | Despicable Me | $251,639,815 | 3,602 | $56,397,125 | 3,476 | Jul 9, 2010 | Universal Pictures |
| 7 | Despicable Me 2021 Re-release | $44,000 | - | - | - | - | Universal Pictures International (UPI) |
